For centuries, the native Guarani Indians of South America have been safely using
Stevia leaves. Stevia has also been safely used for over 30 years, in countries like
Japan, China and Korea as a Cane Sugar Substitute in a wide variety of food products
including sweets, confectionaries, ice creams, soft drinks etc. Extensive experience
and reviews state that Stevia is definitely a safe and a healthy wonder of nature.

Stevia not only has a long history of safe usage but also more than 150 safety studies
and government approvals in more than 20 countries across the world. Stevia has
been scientifically tested and found to be non-toxic, non-carcinogenic, non-mutagenic,
non-teratogenic and devoid of genotoxic effects. Stevia does not affect growth and
reproduction in humans.

 
 
Jan M. C. Geuns, Director of the European Stevia Center in his report concludes:
"The conclusion is that Stevia and Stevioside are safe when used as a sweetener. It is
suited for both diabetics and PKU patients as well as for obese persons intending to
lose weight by avoiding sugar supplements in the diet. No allergic reactions to it seem
to exist."
Molecules of Interest: Stevioside, Phytochemistry 64 (2003) 913-921
 
 
Dr. Mowrey, Director of American Phytotherapy Research Laboratory after going
through the extensive safety studies & reports says:

"Almost every safety test imaginable has been performed on Stevia. The results have
always shown that Stevia is safe. No abnormalities in weight change, food intake, cell
membrane or chromosome characteristics. No cancer, no birth defects, no acute and
no chronic untoward effects. Nothing!"
 
 
    References:
1   Acute Toxicity of Stevioside
Drug. Chem. Toxicol. (1997 Feb-May); 20 (1-2):31-44
Toskulkao C., Chaturat L. et al
     
2   Chronic toxicity of dietary Stevia extracts
Journal of the Food Hygienic Society of Japan (Shokuin Eiseigaku Zasshi).
26 (2). 169-183 (1985)
Yamada A., Ohgaki S. et al
     
3   Chronic Oral Toxicity and Carcinogenecity Study of Stevioside
Chem. Toxic. Vol. 30 No.11, 957-965 (1992)
L. Xili et al
     
4   Assessment of Carcinogenecity of Stevioside
Food and Chem. Toxic. Vol. 35, 597-603 (1997)
K. Toyoda et al
     
5   Effects of three sweeteners in urinary bladder carcinogenesis initiated by
N-butyl-N-nitrosamine

Gann, 75, 763-768 (1986)
Hagiwara A., Fukushuma S.et al
     
6   Teratogenecity study of stevioside
Eisei Shikenjo Hokoku. 113: 31-35 (Japanese) (1995)
Usami M., Sakemi K., Kawashima K et al
     
7   Absence of mutagenesis induced by Stevioside from Stevia rebaudiana Bertoni
Ciencia E Cultura 39(4): 417-418 (1987)
Flores R.Z., Cechin T.Z. et al
     
8   Genotoxity studies of Stevia extract and Steviol by the comet assay
The Journal of Toxicological Sciences, Vol 27 (1): 1-8 (2002)
Sekihashi K., Saitosh H. and Sasaki Yu. F
     
9   Evaluation of the genotoxicity of Stevioside and Steviol using six in vivo and
one in vitro mutagenecity assays

Mutagenesis vol 11 (6): 573-579 (1996)
Matsui M., Matsui K., Kawasaki Y. et al
     
10   Effect of Stevioside on growth and reproduction
Human Reproduction vol.6 no.1 pp. 158-165 (1991).
Yodyingyuad V. and Bunyawong S
     
11   Fertility & Teratogenicity Studies of Stevia rebaudiana
Phytochemistry. 2003 Nov;64(5):913-21
Jan M. C. Geuns
     
12   Molecules of Interest: Stevioside
Phytochemistry 64 (2003) 913-921
Jan M. C. Geuns

If you are a Health Professional and are interested in knowing more about the
Safety Studies on Stevia, feel free to write to us and we will get back to you soon.
 
 
 
 
     
  Stevia Index:
Stevia - The Sweet Leaf
Stevia is Safe
Scientific Data
Safety Studies
   
     
     

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